产品货号：
Z38732
中文名称：
TWEAKR/TNFRSF12A抗体
英文名称：
Anti-TWEAKR/TNFRSF12A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TWEAKR/TNFRSF12A Antibody |
| 指标别名 | TNF receptor superfamily member 12A;CD266;FN14;TWEAKR;TNFRSF12A |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IP |
| 基因名称 | TNFRSF12A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human TWEAKR |
| 实际分子量 | 14KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The gene for TNFRSF12A was initially recognized as a fibroblast growth factor inducible immediate early response gene Fn14 in mouse NIH 3T3 fibroblasts.This gene is mapped to 16p13.3.Human TNFRSF12A cDNA encodes a 129 amino acid residue type I transmembrane protein with a 27 aa signal peptide,a 53 aa extracellular domain,a 21 aa transmembrane domain and a 28 aa cytoplasmic domain.Human and mouse TNFRSF12A hold 82% aa sequence identity.TNFRSF12 is the tiniest member of the TNF receptor superfamily and has only one cysteine rich region in its extracellular domain.The TNFRSF12A cytoplasmic domain holds one TRAF binding motif which binds TRAFs 1,2,and 3.TNFRSF12A binds its ligand TWEAK/TNFSF12A with high affinity to initiate a signal transduction cascade which subject to the cell type,causes different cellular responses such as cell death,cell proliferation,and angiogenesis. |
| Uniprot ID | Q9NP84 |
| 基因名全称 | Tumor necrosis factor receptor superfamily member 12A |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocoprecipitation 1:20 |
相关搜索：TWEAKR/TNFRSF12A抗体，TWEAKR抗体，TNFRSF12A单抗，Anti-TWEAKR/TNFRSF12A Antibody